Steroid eluting stent

If screening tests reveal coronary artery disease, there are steps you can take to lower your risk for having a heart attack or worsening heart disease. Your doctor may recommend lifestyle changes such as a healthier diet, exercise and smoking cessation. Medications may also be necessary. Medicines can treat coronary artery disease (CAD) risk factors such as high cholesterol, high blood pressure, an irregular heartbeat and low blood flow. In some cases, more advanced treatments and surgical procedures can help restore blood flow to the heart.

Chen and colleagues (2014) evaluated the safety and effectiveness of Ex-PRESS implantation (Ex-PRESS) compared to trabeculectomy in the treatment of patients with OAG.  A comprehensive literature search using the Cochrane Methodology Register to identify randomized controlled clinical trials (RCCTs) comparing Ex-PRESS to trabeculectomy in patients with OAG.  Efficacy estimates were measured by weighted mean difference (WMD) for the percentage IOP reduction (IOPR%) from baseline to end-point, and odds ratios (OR) for the complete success rate and post-operative interventions.  Safety estimates were measured by OR for post-operative complications.  Statistical analysis was performed using the RevMan software.  A total of 4 RCCTs were selected for this meta-analysis, including 215 eyes of 200 patients (110 eyes in the Ex-PRESS group, 105 eyes in the trabeculectomy group).  There was no significant difference between Ex-PRESS and trabeculectomy in the IOPR%.  The pooled OR comparing Ex-PRESS to trabeculectomy for the complete success rate at 1 year after surgery were in favor of Ex-PRESS.  The Ex-PRESS procedure was found to be associated with lower number of post-operative interventions and with a significantly lower frequency of hyphema than trabeculectomy, whereas other complications did not differ statistically.  The authors concluded that in OAG, Ex-PRESS and trabeculectomy provided similar IOP control, but Ex-PRESS was more likely to achieve complete success, with fewer post-operative interventions.  Complication rates were similar for the 2 types of surgery, except for a lower frequency of hyphema in the Ex-PRESS group.

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Some FDA regulated products are intended to be used together to achieve their therapeutic or diagnostic effect but do not meet the regulatory definition of a combination product, This can be the case for medical products intended to be used together, for example, syringes marketed for general delivery of unspecified drugs or two or more of the same type of medical product (., a drug and drug, or device and device) that are packaged or labeled for use with one another (., fixed dose combination drugs under 21 CFR ). Similarly, combinations of a medical product with a non-medical product, for example a drug with a dietary supplement, cosmetic, or food, are not combination products.

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Steroid eluting stent

steroid eluting stent

Some FDA regulated products are intended to be used together to achieve their therapeutic or diagnostic effect but do not meet the regulatory definition of a combination product, This can be the case for medical products intended to be used together, for example, syringes marketed for general delivery of unspecified drugs or two or more of the same type of medical product (., a drug and drug, or device and device) that are packaged or labeled for use with one another (., fixed dose combination drugs under 21 CFR ). Similarly, combinations of a medical product with a non-medical product, for example a drug with a dietary supplement, cosmetic, or food, are not combination products.

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