Other common diseases that result from endocrine dysfunction include Addison’s disease , Cushing’s disease and Grave’s disease . Cushing's disease and Addison's disease are pathologies involving the dysfunction of the adrenal gland. Dysfunction in the adrenal gland could be due to primary or secondary factors and can result in hypercortisolism or hypocortisolism . Cushing’s disease is characterized by the hypersecretion of the adrenocorticotropic hormone (ACTH) due to a pituitary adenoma that ultimately causes endogenous hypercortisolism by stimulating the adrenal glands.  Some clinical signs of Cushing’s disease include obesity, moon face, and hirsutism.  Addison's disease is an endocrine disease that results from hypocortisolism caused by adrenal gland insufficiency. Adrenal insufficiency is significant because it is correlated with decreased ability to maintain blood pressure and blood sugar, a defect that can prove to be fatal. 
I am hoping to hear from some of you, if you have the same concerns or if surgery has been successful. I am worried about doing something that will cause permanent limitations leaving me no better off than I am. Is it unrealistic to hope to return to the things I love like gardening, mountain biking, scuba diving, canoeing, aerobics, hiking, dancing, camping, fly fishing? How soon can I go back to work? (I now work with water conservation/irrigation consulting and must walk and bend, but not work physically hard.) I'm confused that there is a difference of opinion between doctors if they will straighten the spine or fuse it as it is, what is the length of recovery time, and exactly how they will do this.
In the present study, the extra morbidity of iliac crest harvesting was avoided by using bone morphogenetic protein. We chose to use a half sponge in each of the defects based on the space available, but this dose has not been studied for this particular application. Other options would be to use autograft bone or demineralized bone matrix. The minimally invasive approach limits paraspinal muscle damage and optimizes early return to play while accomplishing a direct repair of the defect. In conclusion, a minimally invasive modification of the Buck’s screw technique for direct repair of isthmic spondylolysis as presented here offers an excellent option to young active adults by minimizing muscle injury and preserving the adjacent joint.